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ShedRx vs TMates — GLP-1 Comparison 2026

Which GLP-1 telehealth program is right for you?

Quick answer

ShedRx and TMates both offer GLP-1 telehealth, but they package medication, support, and pricing differently. The right choice depends on whether you weight cost, clinical touch, or formulation flexibility highest.

Side-by-side comparison

FeatureShedRxTMates
Best forBroad GLP-1 menu and multiple formatsCompounded GLP-1 with hands-on clinical touch
Medication typeCompounded and brand-name optionsCompounded GLP-1 with bundled clinical support
Pricing modelStarting prices by productMonthly subscription, dose-tier pricing
Semaglutide priceFrom $175/moFrom $179/mo
Tirzepatide priceFrom $245/moFrom $249/mo
Key watchoutVerify higher-dose pricing and exact formulation before checkoutConfirm what the higher tiers include vs the entry tier

When to choose ShedRx

  • You want both compounded and brand-name options on one menu
  • You prefer multiple formulation formats (injection, oral, sublingual where offered)
  • You're starting at a low dose and want a low entry price
  • You value being able to switch products without changing programs

Check current ShedRx pricing →

When to choose TMates

  • You want a compounded program with clinical check-ins built in
  • You'd rather pay one bundled monthly fee than line items
  • You want responsive messaging with prescribers
  • You're comfortable with a longer onboarding intake in exchange for support

Check current TMates pricing →

Full reviews

Frequently asked questions

Is ShedRx cheaper than TMates?

ShedRx starts lower on semaglutide (From $175/mo). ShedRx starts lower on tirzepatide (From $245/mo). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.

Which is better for semaglutide or tirzepatide — ShedRx or TMates?

ShedRx starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.

Are ShedRx and TMates compounded or brand-name?

ShedRx offers compounded and brand-name options. TMates offers compounded glp-1 with bundled clinical support. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.

Can I switch from ShedRx to TMates?

Yes — switching between ShedRx and TMates is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.

Compare ShedRx and TMates to other programs

RangeYourself is reader-supported. We may earn a commission when you click on certain links — at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like $175/mo and $179/mo are starting tiers, not your guaranteed long-term cost.